Chiral Chromatography

In many biological processes, the activity of one member of an enantiomeric pair can be contrasted with the inactivity or even harmful activity of the other. The successful development of chiral stationary phases (CSPs) for HPLC and SFC, allows us to monitor the optical purity of a bulk drug and its presence in formulations or biological fluids. Further applications can be found within the agrochemical and related industries. The main types of CSPs include Immobilised Polysaccharide, Cellulose and Amylose Bound, ‘Brush-Type’, Protein Bound, Cyclodextrin Inclusion, Crown Ether, Ligand Exchange and Network Polymeric.

Chiral Overview

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